Phosphatidylserine (PS)

Phosphatidylserine (PS) is a phospholipidic component of the membrane that envelops brain cells. PS helps maintain the permeability of fluid in the brain cell and controls the flow of fluid through the cell membrane.

Nootropic Score


Phosphatidylserine is involved in the formation and transmission of signals between nerve cells. This chemical signaling is carried out via neuronal synapses. It is responsible for many of the chemical and biological functions of brain cells, such as the production of neurotransmitters and neurotransmitter receptors.

Phosphatidylserine is involved in the formation of mitochondria, which are the energy centers of brain cells. PS promotes healthy nerve growth factor (NGF) and supports the neurogenesis required for long-term potentiation (LTP). Memory formation depends on healthy LTTP, and PS increases the number of neurons in a brain cell and promotes the development of new neurons by supporting healthy nerves and the growth of nerve growth factors, N GF.

Essential Nootropic

Phosphatidylserine (PS) is probably one of the most effective and essential nootropics we have today. PS keeps the brain healthy and promotes new nerve cells and the growth of nerve growth factors, N GF.

It can improve attention, cognition, memory, memory, and mood as well as mood and mental health.

Neuroplasticity, which helps neurons form new connections necessary for memory formation. Phosphatidylserine (PS) keeps fluid-permeable and supports the creation of new neurons and the development of neurons.

Interaction with Choline

Phosphatidylserine is a phospholipid containing choline precursor acetylcholine (ACh) and is responsible for the production of the neurotransmitters dopamine, serotonin, and norepinephrine in the brain. PS increases mental energy by facilitating the release of glucose and oxygen needed to supply brain cells and increases the A-Ch level in mind, according to the National Institutes of Health.

Phosphatidylserine works in conjunction with DHA (omega-3) in cells and keeps brain cells optimized for the neurotransmitters dopamine, serotonin, and norepinephrine in the brain.

Phosphatidylserine (PS) is a phospholipid component of the membrane of brain cells. The membrane layer is the outer shell that surrounds the cell and acts as a protective barrier between the cells and the outside world.

Phosphatidylcholine (PC) is the most common phospholipid in the brain, followed by slightly lower phosphatidylserine levels. PS plays a crucial role in cell-to-cell signaling in our brain, and it is necessary to maintain the fluid within the cell membrane.

Cellular Membrane Interaction

PC is located in the outer layer of the membrane of brain cells, and PS is part of an inner layer. The balance of these two phospholipids and their respective PS and PC levels is crucial for maintaining optimal cognitive health.

Phosphatidylserine (PS) supports the formation and transmission of neuronal signals between neurons. In the brain, PS is synthesized by replacing the base group with serine, and PC synapses by PS in synaptic crossings that connect one neuron to another.

Phosphatidylserine (PS) also helps produce nerve growth factor (NGF), which ensures healthy neurogenesis. This cellular communication is the way memories are formed and the basis for the formation of new neurons.

Natural Decline

Phospholipids, including phosphatidylserine (PS), begin to decline until 20% is reached. PS even helps to build up mitochondria, which are the energy source of a brain cell. When the membranes of brain cells are healthy, they are malleable, fluid, and flexible.

The shell begins to harden, but only after a certain amount of phosphatidylserine (PS) and other phospholipids (PPS) and then only up to about 20%.

The structure and function of the cell depend on an ideal fat balance, including cholesterol. The good news is that it can prevent cellular damage, but only after a certain amount of phosphatidylserine (PPS).

Without the right balance, the function of the cell membrane is impaired, and a typical modern diet does not provide enough phosphatidylserine to maintain the health of brain cells.

PS in Nature

Phosphatidylserine (PS) is produced naturally, but unfortunately, not many of us include organs and meat in our daily diet. For this reason, we experience high levels of inflammation in the brain and high blood pressure and heart disease. One of the best ways to maintain healthy phosphate levels (PS) in your mind is to take PS as a nootropic or dietary supplement.

PS was initially made from cow brains, but some PS supplements are now made with extracts of soy, sunflower, and lecithin due to mad cow disease.

Phosphatidylserine promotes brain health and function in various ways, such as brain cell development, neuron formation, and nerve cell repair.

Memory Boost

Phosphatidylserine is one of the most effective memory boosters known and is needed for memory. PS stimulates serotonin production, a brain chemical that stimulates neuronal signals for fast and clear thinking. Two stand out: the first in the form of an increase in brain activity and the second in forming new brain cells.

PS has shown that it can slow, stop, or reverse the cognitive decline of age. In a study of 149 patients who met the criteria for age-associated memory problems – they were given 100 mg of phosphatidylserine or a placebo for 12 weeks. Patients who received PS showed significant improvements in tests related to learning, memory, tasks, and daily life.

Interactions with Omega-3

This type of fat is obtained by absorbing omega-3 fatty acids, and the brain is mostly made up of DHA fats. PS works with D HA (omega 3) to protect brain cells from damage and helps to form healthy blood vessels.

Researchers in Canada who examined samples from the Memory and Aging Project found a link between DHA levels in the brain and Alzheimer’s. The study showed that a decline in D-HA levels, especially in brain cells, is associated with Alzheimer’s disease and leads to cognitive impairment.

The team found that both DHA and phosphatidylserine are responsible for a decline in neurotransmitters dopamine, serotonin, and norepinephrine in Alzheimer’s.

Scientific Studies

These studies and clinical studies provide ample motivation to supplement phosphatidylserine and DHA with the anti-inflammatory and anti-inflammatory properties of these two substances. Both help ward off neurodegenerative diseases, and clinical trial after clinical trial provides evidence of the benefits of supplementing with both.

Changes that can occur in old age and that can occur at any age until adulthood, cause the brain to optimize its response to environmental changes such as stress and stressors.

The cell membranes are influenced by the environment, such as the food we eat, the air we breathe, and the weather. From our twenties onwards, we experience changes in the cell membrane structure and structure of brain cells.

Phosphatidylserine (PS) can, therefore, help with age-related cognitive decline and students who want to do better at school.

Phosphatidylserine (PS) is responsible for over 80% of the total phosphate content in the human body. It is found in several organs, including the brain, heart, liver, kidneys, lungs, and liver. PS is modulated and involved in many different aspects of human health, as well as in the areas of health and nutrition.

Healthy brain cell membranes support neuroplasticity so that neurons can make the connections needed to turn new experiences into memories. Also, the intake of phosphatidylserine improves brain function, which tends to decline with age.


When phosphatidylserine is used as nootropics, motivation, socialization, and initiative increase, many clinical studies with PS have shown a positive effect on the development of cognitive function and mental health. PS is even effective in reducing stress and helps to lower cortisol and ACTH levels during intense physical activity. In combination with other nootropic medications, PS can cause a reduction in blood pressure and heart rate.

The effects of phosphatidylserine on the development of cognitive function and mental health: an overview of the scientific literature.

Phosphatidylserine (PS) is an excellent addition to ADHD drugs, and there are reports that PS helps with Tourette’s syndrome. PS helps to tame the symptoms of ADHD and treat obsessive-compulsive disorder (ADHD).

You may even be able to restrict your ADHD medication to where phosphatidylserine accumulates in your system. Popular stimulants such as Ritalin and Adderall do not bother you but can cause serious side effects such as hyperactivity and impulsiveness.

It would be unpleasant to be continuously agitated, but a study in Germany gave 16 healthy volunteers phosphatidylserine (PS) for 42 days. Beta brain currents have a positive effect on the brain’s ability to produce brain currents in your mind. Beta waves are associated with concentration, arousal, alertness, and cognition.

Long-term Enhancement

The most important result of the study was that chronic phosphatidylserine supplementation significantly reduced the beta-brain currents. The team tested brain wave patterns before and after supplementation, but not after. Another study showed that phosphatidylserine dampens the release of cortisol in response to stress.

In another study, researchers at the University of Wales in Swansea gave young adults 300mg of phosphatidylserine daily. The study found that they felt less stressed during a strenuous math task.

The researchers concluded that PS supplementation improves mood and reduces stress, even in healthy young people. The longer the supplement lasted, the better the bee meat, the study authors said.


To cope with changes in pressure and pH, cell membranes must have fatty acids that help them to be fluid, bend, and stretch under pressure, rather than disintegrate. It would require several large portions daily to discuss all therapeutic effects, but phosphatidylserine works by absorbing omega-3 fatty acids, which have their functions to improve memory and mental health. But to get the most significant benefits from PS, a supplement is needed. It would have taken several more substantial daily portions of food to achieve all the therapeutic effects we have discussed. [Sources: 4]

This envelope is essential to protect neurons and accelerate the transmission of electrical impulses, which is crucial for brain function. Recently, phosphatidylserine has been found to improve neuronal function and help restore damaged neurons to normal function. Its ability to activate necessary signal transmission and modulate the release of signals has renewed interest in its relationship to brain functions 3, 5. [Sources: 4, 5]

The acetyl cocoa of choline consists of two different phosphatidylserine types, acetylcholine, and acetaldehyde, which is why it is often contained in the Nootropic Stack [7]. [Sources: 5]

Serotonin is associated with good mood and improved sleep, but sometimes depression can be the result of a deficiency. Serotonin deficiency is strongly associated with depression and poor concentration, and as we age, we forget it more and more [8]. [Sources: 1, 5]

PS supplements can compensate for natural defects that occur and absorb part of old age-associated memory problems [9]. Also, functional studies show a positive effect of PS supplements on depression-related symptoms such as improved mood [10]. [Sources: 1]

Consider that most of the phosphatidylserine used in these studies are derived from the brain cells of cows, but most dietary supplements are made from soy or cabbage. Remember that it is a phospholipid that combines serine amino acids, so it should be taken on an empty stomach to achieve the best absorption. [Sources: 1, 6]

In all studies conducted to date, participants complained of significant side effects and developed nausea in some cases. Preliminary studies have shown that plant phosphatidylserine supplements can also offer benefits (a 2010 study on memory, for example, soy-based phosphatidylserine), but more research is needed. Although some have suggested its limited effect, it does not appear to be the current focus of research. [Sources: 1, 6]

Some studies have confirmed that PS supplements based on soy protein, such as soy protein powder, have the same effect as PS supplements made from cow’s brain. [Sources: 1]

Phosphatidylserine, commonly known as PS, is a fat-soluble substance called phospholipid that is already present in all humans’ brain tissue. It is a substance that helps the brain release chemicals that transmit signals to nerve cells. The normal viscosity of the cell membrane is influenced by the enzyme that binds to the membrane. There is the ability to disrupt the mechanism of enzymatic activity and transport. [Sources: 1, 2]

Although the nutritional supplements used contain components other than PS, it is claimed that the current results are due solely to the effect of PS. There is evidence that PS and 35% PS, which restore dopamine secretion, also improve the neurotransmission of glutamic acid. About 36% of these effects on neurotransmission may be related to the impact of PS on depression. [Sources: 2]

It is not clear whether this is related to membrane function, and therefore omega-3 fatty acids may play an essential role in the present results. However, if this is the case in rat studies, then they could also affect preventing forced swimming. Another theory is that additional PS accumulates in the heart tissue, improving the contractibility of heart tissue, as shown in some rat studies, and thus improving performance. [Sources: 0, 2]

Numerous studies have concluded that PS is safe, and although further evidence is needed, it seems that experiments with PS have nothing to lose. Indeed, the only side effects appear to be beneficial, such as improved mental acuity and a reduction in circulating stress hormones. Further research is also needed to unravel whether PS can act as an antioxidant or reduce the risk of heart disease, cancer, diabetes, heart failure, and cardiovascular disease. Athletes and their coaches should look for new research in this exciting area – there are many more ways to learn about the benefits PS can offer, so choose your experiments wisely. [Sources: 0]

Research suggests that PS can help with symptoms of cognitive decline in the field of memory, especially to help people retrieve information more quickly. This benefit is most noticeable when people are tired or engage in physical activity such as exercise. In a broader sense, this could indicate that the intake of PS is something athletes should pay attention to, although non-athletes can undoubtedly benefit. [Sources: 3]

Part of what might explain this benefit is that the nutrient increases the amount in the body, not only the amount but also the quality of it. [Sources: 3]

Leave a Reply
Previous Article

The Entrepreneur's Guide to Nootropics: Scaling Your Startup Productivity

Next Article

Best Nootropics

Related Posts